Description

3,4-Piperidinediol, 5-(Hydroxymethyl)-, (3S,4S,5S)- (9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. This compound matters because it provides a rigid, functionalized scaffold with multiple hydroxyl groups, enabling precise molecular construction for complex target molecules. It is primarily needed by pharmaceutical and biotechnology R&D teams for the development of new active pharmaceutical ingredients (APIs), particularly in areas like neurology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Chemical Biology Probe Synthesis: Used to construct molecular probes for studying biological pathways and target engagement due to its defined stereochemistry and functional handles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in enantioselective catalytic reactions.
• Advanced Material Research: Investigated as a monomer or functional component in the development of specialty polymers with specific stereochemical properties.
• Academic & Industrial R&D: Employed in discovery chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	3,4-Piperidinediol, 5-(Hydroxymethyl)-, (3S,4S,5S)- (9Ci)
CAS No.	319924-35-1
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(3S,4S,5S)-5-(Hydroxymethyl)piperidine-3,4-diol; (3S,4S,5S)-5-(Hydroxymethyl)-3,4-piperidinediol; 5-(Hydroxymethyl)-3,4-piperidinediol (3S,4S,5S)-; 1-Aza-2,3,5-trideoxy-5-C-(hydroxymethyl)-D-erythro-hexitol; (3S,4S,5S)-5-(Hydroxymethyl)-1-azacyclohexane-3,4-diol; A stereoisomer of DAB (1,4-dideoxy-1,4-imino-D-arabinitol) derivative; Chiral Piperidinetriol Derivative
EINECS	Contact for details

Quality Control

Our 3,4-Piperidinediol, 5-(Hydroxymethyl)-, (3S,4S,5S)- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity by HPLC, chiral purity, and residual solvent levels are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.