Description

4-(1-Piperazinyl)-3-Trifluoromethylbenzenamine is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and trifluoromethyl-substituted aniline structure. This compound matters for its critical role in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in neurological and psychiatric drug discovery.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, leveraging the bioactivity of the trifluoromethyl group.
• Organic Synthesis: Serves as a versatile precursor for creating complex molecules in medicinal chemistry and material science.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method development.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalytic processes and metal-organic frameworks.

Basic Information

Product Name	4-(1-Piperazinyl)-3-Trifluoromethylbenzenamine
CAS No.	319474-60-7
Molecular Formula	C11H14F3N3
Molecular Weight	245.25 g/mol
Synonyms	3-Trifluoromethyl-4-piperazin-1-yl-aniline; 4-Piperazin-1-yl-3-(trifluoromethyl)aniline; 1-(4-Amino-2-(trifluoromethyl)phenyl)piperazine; Benzenamine, 4-(1-piperazinyl)-3-(trifluoromethyl)-; 4-Amino-2-(trifluoromethyl)phenylpiperazine
EINECS	Contact for details

Quality Control

Our 4-(1-Piperazinyl)-3-Trifluoromethylbenzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.