Description

4-Cbz-2-(Aminomethyl)Morpholine is a high-purity, protected morpholine derivative featuring a carboxybenzyl (Cbz) protecting group on the amine functionality. This compound is a critical pharmaceutical intermediate and building block in organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those containing morpholine and amine pharmacophores.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology: Employed as a probe or linker in the development of chemical tools for studying biological systems.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	4-Cbz-2-(Aminomethyl)Morpholine
CAS No.	317365-31-4
Molecular Formula	C13H18N2O3
Molecular Weight	250.30 g/mol
Synonyms	2-(Aminomethyl)-4-[(benzyloxy)carbonyl]morpholine; 4-[(Benzyloxy)carbonyl]-2-(aminomethyl)morpholine; 4-Carbobenzoxy-2-(aminomethyl)morpholine; 4-Cbz-2-(aminomethyl)morpholine; N-Cbz-2-(aminomethyl)morpholine; 2-(Aminomethyl)morpholine-4-carboxylic acid benzyl ester; Benzyl 2-(aminomethyl)morpholine-4-carboxylate; 317365-31-4
EINECS	Contact for details

Quality Control

Our 4-Cbz-2-(Aminomethyl)Morpholine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.