Description

Rosiglitazonepotassiumsalt CAS NO 316371-84-3 is the potassium salt form of Rosiglitazone, a thiazolidinedione-class compound. This high-purity intermediate is critical for ensuring the efficacy and consistency of final pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of antidiabetic medications and related metabolic disorder therapies.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the commercial manufacturing of Rosiglitazone maleate, the active component in antidiabetic drugs.
• Pharmaceutical R&D: Used in preclinical and clinical research for developing new Type 2 diabetes mellitus treatments and studying peroxisome proliferator-activated receptor gamma (PPAR-γ) agonists.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Metabolic Research: Employed in biochemical studies to investigate insulin sensitization, glucose metabolism, and adipocyte differentiation.
• Formulation Development: Utilized in the development of novel drug delivery systems for improved bioavailability and stability of Rosiglitazone-based therapies.

Basic Information

Product Name	Rosiglitazonepotassiumsalt
CAS No.	316371-84-3
Molecular Formula	C18H19KN2O3S
Molecular Weight	382.52 g/mol
Synonyms	Rosiglitazone Potassium Salt; 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione Potassium Salt; (±)-5-[[4-[2-(Methyl(2-pyridinyl)amino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione Monopotassium Salt; Rosiglitazone Potassium; Avandia Intermediate Potassium Salt; BRL 49653 Potassium Salt; PPARγ Agonist Potassium Salt
EINECS	Contact for details

Quality Control

Our Rosiglitazonepotassiumsalt is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and NMR. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure full traceability and compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.