Description

(S)-4-n-Boc-Piperazine-2-Carboxylic Acid Methyl Ester CAS NO 314741-39-4 is a high-purity chiral piperazine derivative, serving as a critical building block in modern organic synthesis. Its value lies in providing a protected, stereochemically defined scaffold essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid motifs into peptide backbones to enhance stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing chiral ligands and organocatalysts.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A fundamental component for custom synthesis organizations (CSOs) producing bespoke compounds for client R&D programs.
• Academic Research: Utilized in university and institutional labs for methodological development in stereoselective synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-4-n-Boc-Piperazine-2-Carboxylic Acid Methyl Ester
CAS No.	314741-39-4
Molecular Formula	C12H22N2O4
Molecular Weight	258.32 g/mol
Synonyms	(S)-Methyl 4-(tert-butoxycarbonyl)piperazine-2-carboxylate; (S)-1-Boc-4-Piperazinecarboxylic Acid Methyl Ester; (S)-1-tert-Butyl 2-Methyl 1,2-Piperazinedicarboxylate; (S)-1-(tert-Butoxycarbonyl)piperazine-2-carboxylic Acid Methyl Ester; (S)-Boc-Pip(2)-OMe; (S)-Boc-Piperazine-2-COOMe; (S)-4-Boc-Piperazine-2-Carboxylic Acid Methyl Ester; (S)-N-Boc-Piperazine-2-Carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (S)-4-n-Boc-Piperazine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.