Description

1,2,4-Piperazinetricarboxylic Acid,4-(1,1-Dimethylethyl)2-Methyl1-(Phenylmethyl)Ester,(2S)- is a high-purity, stereochemically defined piperazine derivative used as a critical building block in advanced organic synthesis. Its value lies in providing a protected, multifunctional scaffold that enables the efficient construction of complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Acts as a constrained dipeptide analog or scaffold in the design of peptide mimics for drug discovery.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, specialty chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	1,2,4-Piperazinetricarboxylic Acid,4-(1,1-Dimethylethyl)2-Methyl1-(Phenylmethyl)Ester,(2S)-
CAS No.	314741-38-3
Molecular Formula	C20H28N2O4
Molecular Weight	360.45 g/mol
Synonyms	(2S)-1-Benzyl-4-(tert-butyl) 2-methyl 1,2,4-piperazinetricarboxylate; 1-Benzyl-4-tert-butyl 2-methyl (2S)-1,2,4-piperazinetricarboxylate; (S)-1-Benzyl-4-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate; tert-Butyl 1-benzyl 2-methyl (2S)-1,2,4-piperazinetricarboxylate; (S)-1,2,4-Piperazinetricarboxylic Acid 1-Benzyl 4-tert-Butyl 2-Methyl Ester; CAS 314741-38-3
EINECS	Contact for details

Quality Control

Our 1,2,4-Piperazinetricarboxylic Acid derivative is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.