Description

Migrastatin CAS NO 314245-65-3 is a potent and selective macrocyclic ketone natural product known for its significant anti-metastatic properties. This compound matters for its targeted inhibition of tumor cell migration and invasion, offering a promising research pathway for novel cancer therapeutics. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology drug discovery and metastasis research.

Application

• Oncology Research & Drug Discovery: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of anti-metastatic cancer therapies.
• Biochemical Mechanism Studies: Used to investigate cellular migration pathways, actin cytoskeleton dynamics, and the molecular mechanisms of metastasis.
• Pharmacological Screening: Serves as a positive control or lead compound in high-throughput screening assays for anti-migratory activity.
• Academic & Institutional Research: Employed in university and hospital laboratories for fundamental cancer biology and translational medicine studies.
• Preclinical Development: Utilized in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles of anti-metastatic agents.

Basic Information

Product Name	Migrastatin
CAS No.	314245-65-3
Molecular Formula	C₂₃H₃₀O₅
Molecular Weight	386.48 g/mol
Synonyms	Migrastatin; (-)-Migrastatin; L-755,805; Antibiotic L 755805; (3S,5R,6S,8R,9E,11S,12R,14S)-5,6,14-Trihydroxy-3,11-dimethoxy-8,12-dimethyl-1-oxacyclotetradeca-9,13-dien-2-one
EINECS	Contact for details

Quality Control

Our Migrastatin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.