Description

(2R)-1-(3-Chloro-2-Pyrazinyl)-2-Methylpiperazine is a high-purity chiral piperazine derivative and a key pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily needed by pharmaceutical R&D laboratories, process chemistry teams, and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex target molecules, particularly in medicinal chemistry.
• Asymmetric Catalysis Research: Serves as a ligand precursor or chiral auxiliary in the development of stereoselective synthetic methodologies.
• Preclinical & Clinical Trial Material Production: Supplied under controlled conditions for the manufacture of compounds used in non-clinical and clinical studies.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production of advanced intermediates.

Basic Information

Product Name	(2R)-1-(3-Chloro-2-Pyrazinyl)-2-Methylpiperazine
CAS No.	313657-76-0
Molecular Formula	C9H13ClN4
Molecular Weight	212.68 g/mol
Synonyms	(R)-1-(3-Chloro-2-pyrazinyl)-2-methylpiperazine; (2R)-2-Methyl-1-(3-chloro-2-pyrazinyl)piperazine; 1-(3-Chloro-2-pyrazinyl)-2-methyl-(2R)-piperazine; (R)-2-Methyl-1-(3-chloro-pyrazin-2-yl)piperazine; 313657-76-0; UNII-9V8V3WY4Q5; 9V8V3WY4Q5; SCHEMBL2184225
EINECS	Contact for details

Quality Control

Our (2R)-1-(3-Chloro-2-Pyrazinyl)-2-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.