Description

(R)-4-n-Trityl-2-Methyl Piperazine is a high-purity chiral piperazine derivative, a critical building block in modern asymmetric synthesis. Its value lies in providing a sterically hindered, enantiomerically pure scaffold for constructing complex pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors who require precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand: Serves as a sophisticated ligand framework for transition metal catalysts used in enantioselective transformations.
• Agrochemical Synthesis: Building block for creating novel, stereochemically defined pesticides and herbicides with enhanced efficacy.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable tool for method development and exploring new reaction pathways in organic and medicinal chemistry.
• Material Science: Potential monomer or additive for creating chiral polymers and advanced functional materials.

Basic Information

Product Name	(R)-4-n-Trityl-2-Methyl Piperazine
CAS No.	313657-75-9
Molecular Formula	C24H26N2
Molecular Weight	342.48 g/mol
Synonyms	(R)-4-Trityl-2-methylpiperazine; (R)-2-Methyl-4-tritylpiperazine; (R)-4-(Triphenylmethyl)-2-methylpiperazine; (R)-N-Trityl-2-methylpiperazine; (R)-1-Trityl-3-methylpiperazine; (R)-4-Trityl-2-pipecoline; (R)-α-Methyl-4-tritylpiperazine
EINECS	Contact for details

Quality Control

Every batch of (R)-4-n-Trityl-2-Methyl Piperazine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming critical parameters such as chiral purity (enantiomeric excess), chemical purity, and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.