Description

3,5-Dichloropyrazine-2-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive dichloro and cyano substituents, which enable precise molecular construction for creating complex, high-value compounds. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its pyrazine core for bioactivity.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in catalysis and material science.
• Functional Material Research: Employed in the creation of organic electronic materials, dyes, and pigments due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functionalization on a pyrazine ring.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3,5-Dichloropyrazine-2-Carbonitrile
CAS No.	313339-92-3
Molecular Formula	C5H1Cl2N3
Molecular Weight	173.98 g/mol
Synonyms	2-Cyano-3,5-dichloropyrazine; 3,5-Dichloro-2-pyrazinecarbonitrile; 3,5-Dichloropyrazinecarbonitrile; Pyrazine-2-carbonitrile, 3,5-dichloro-; 3,5-Dichloro-2-cyanopyrazine
EINECS	Contact for details

Quality Control

Our 3,5-Dichloropyrazine-2-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.