Description

9-Hydroxy-3,7-Diaza-Bicyclo[3.3.1]Nonane-3-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique diazabicyclononane scaffold. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained bicyclic structure and functional groups.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	9-Hydroxy-3,7-Diaza-Bicyclo[3.3.1]Nonane-3-Carboxylic Acid tert-Butyl Ester
CAS No.	313238-53-8
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	3-(tert-Butoxycarbonyl)-3,7-diazabicyclo[3.3.1]nonan-9-ol; 9-Hydroxy-3,7-diazabicyclo[3.3.1]nonane-3-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 9-hydroxy-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate; 3,7-Diazabicyclo[3.3.1]nonane-3-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester; 9-Hydroxy-3,7-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid tert-butyl ester; BOC-9-OH-3,7-Diazabicyclo[3.3.1]nonane; 3-Boc-9-hydroxy-3,7-diazabicyclo[3.3.1]nonane
EINECS	Contact for details

Quality Control

Our 9-Hydroxy-3,7-Diaza-Bicyclo[3.3.1]Nonane-3-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.