Description

[4-(4-Chloro-Benzyl)-Piperazin-1-Yl]-Acetic Acid Dihydrochloride is a high-purity, synthetically derived chemical building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop novel bioactive compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex APIs requiring a functionalized piperazine-acetic acid core.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.
• Academic Research: Employed in university and institutional laboratories for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	[4-(4-Chloro-Benzyl)-Piperazin-1-Yl]-Acetic Acid Dihydrochloride
CAS No.	313235-14-2
Molecular Formula	C₁₃H₁₈Cl₂N₂O₂
Molecular Weight	305.20 g/mol
Synonyms	2-[4-[(4-Chlorophenyl)methyl]piperazin-1-yl]acetic acid dihydrochloride; 1-[(4-Chlorobenzyl)piperazin-1-yl]acetic acid dihydrochloride; [4-(p-Chlorobenzyl)piperazin-1-yl]acetic acid dihydrochloride; 4-(4-Chlorobenzyl)piperazine-1-acetic acid dihydrochloride; (4-(4-Chlorobenzyl)piperazin-1-yl)acetic acid hydrochloride (1:2); Acetic acid, 2-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our [4-(4-Chloro-Benzyl)-Piperazin-1-Yl]-Acetic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.