Description

1-[4-(4-Nitrophenyl)Piperazino]-3-Phenoxy-2-Propanol is a high-purity synthetic organic compound belonging to the phenoxypropanolamine class, serving as a critical intermediate in advanced pharmaceutical research and development. Its molecular structure, featuring a nitrophenylpiperazine moiety, makes it a valuable building block for creating novel bioactive molecules targeting specific receptors. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of potential therapeutic agents, particularly in the areas of neurological and cardiovascular research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Biochemical Research: Used as a reference standard or ligand in receptor binding studies and pharmacological assays to investigate adrenergic or serotonergic pathways.
• Organic Synthesis Building Block: Employed in medicinal chemistry for the development of new chemical entities (NCEs) due to its versatile piperazine and phenoxypropanol functional groups.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and metabolic pathways.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up development.

Basic Information

Item	Details
Product Name	1-[4-(4-Nitrophenyl)Piperazino]-3-Phenoxy-2-Propanol
CAS No.	312529-68-3
Molecular Formula	C19H23N3O4
Molecular Weight	357.41 g/mol
Synonyms	3-Phenoxy-1-[4-(4-nitrophenyl)-1-piperazinyl]-2-propanol; 1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-phenoxypropan-2-ol; 4-(4-Nitrophenyl)-1-(2-hydroxy-3-phenoxypropyl)piperazine; Nifenazone Impurity; Phenoxypropanolamine derivative; 312529-68-3; 1-[4-(4-Nitrophenyl)-1-piperazinyl]-3-phenoxy-2-propanol
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Nitrophenyl)Piperazino]-3-Phenoxy-2-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high standards of chemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.