Description

1-(4-Fluorobenzyl)Piperazin-2-One is a high-purity fluorinated piperazinone derivative, a crucial building block in modern synthetic organic chemistry. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated pharmacophores into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorobenzyl moiety can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a probe or building block in the synthesis of compounds for studying biological pathways and protein interactions.
• Material Science: Potential intermediate for the synthesis of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	1-(4-Fluorobenzyl)Piperazin-2-One
CAS No.	309915-37-5
Molecular Formula	C11H13FN2O
Molecular Weight	208.23 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-2-piperazinone; 1-(4-Fluorobenzyl)-2-piperazinone; 2-Piperazinone, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)piperazin-2-one; 4-Fluorobenzylpiperazinone; 309915-37-5; 1-(4-Fluorobenzyl)-2-piperazinone; 1-(p-Fluorobenzyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.