Description

4-(4-Methylphenyl)-n-[(Z)-Thiophen-2-Ylmethylidene]Piperazin-1-Amine is a specialized organic compound featuring a piperazine core substituted with a thiophene-derived imine and a p-tolyl group, making it a valuable intermediate for advanced chemical synthesis. This compound's unique structure provides a versatile scaffold for constructing complex molecules with potential biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry, lead optimization, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Research: Used in the development of new pesticides, herbicides, or fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers or organic electronic materials.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex piperazine and thiophene-containing molecular libraries.
• Ligand in Catalysis: Potential use as a chelating ligand in transition metal catalysis for various organic transformations.

Basic Information

Product Name	4-(4-Methylphenyl)-n-[(Z)-Thiophen-2-Ylmethylidene]Piperazin-1-Amine
CAS No.	307348-67-0
Molecular Formula	C17H19N3S
Molecular Weight	297.42 g/mol
Synonyms	1-[(1Z)-2-Thienylmethylene]-4-(4-methylphenyl)piperazine; (Z)-N-((Thiophen-2-yl)methylene)-4-(p-tolyl)piperazin-1-amine; 4-(p-Tolyl)-1-[(thiophen-2-yl)methylidene]piperazine; 307348-67-0; 4-(4-Methylphenyl)-N-[(Z)-thiophen-2-ylmethylidene]piperazin-1-amine; 1-[(2-Thienyl)methylene]-4-(4-methylphenyl)piperazine; 4-(4-Methylphenyl)-1-[(Z)-2-thienylmethylene]piperazine
EINECS	Contact for details

Quality Control

Our 4-(4-Methylphenyl)-n-[(Z)-Thiophen-2-Ylmethylidene]Piperazin-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.