Description

n-[(Z)-(2-Chlorophenyl)Methylidene]-4-(4-Methylphenyl)Piperazin-1-Amine is a specialized organic compound featuring a piperazine core substituted with a chlorophenyl methylidene and a tolyl group, making it a valuable chemical intermediate. This compound is engineered for high-precision synthesis, offering a defined stereochemistry and functional group arrangement critical for advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as by fine chemical manufacturers seeking to develop novel active ingredients or complex molecular architectures.

Application

• As a key synthetic intermediate in the research and development of novel pharmaceutical candidates, particularly in central nervous system (CNS) or receptor-targeted therapies.
• In the design and synthesis of agrochemicals, where its structural motifs can contribute to new herbicides, fungicides, or plant growth regulators.
• For use in academic and industrial research programs focused on medicinal chemistry, chemical biology, and structure-activity relationship (SAR) studies.
• As a building block in fine chemical synthesis for creating complex molecules with specific chiral or steric properties.
• Potential application in the development of dyes, pigments, or functional materials due to its conjugated aromatic system.

Basic Information

Product Name	n-[(Z)-(2-Chlorophenyl)Methylidene]-4-(4-Methylphenyl)Piperazin-1-Amine
CAS No.	307348-62-5
Molecular Formula	C18H18ClN3
Molecular Weight	311.81 g/mol
Synonyms	1-[(Z)-[(2-Chlorophenyl)methylene]amino]-4-(4-methylphenyl)piperazine; 4-(4-Methylphenyl)-1-[(Z)-[(2-chlorophenyl)methylene]amino]piperazine; (Z)-N-[(2-Chlorophenyl)methylidene]-4-(p-tolyl)piperazin-1-amine; 307348-62-5; 1-(4-Methylphenyl)-4-[(Z)-[(2-chlorophenyl)methylidene]amino]piperazine; (Z)-N-(2-Chlorobenzylidene)-4-(4-methylphenyl)piperazin-1-amine
EINECS	Contact for details

Quality Control

Our n-[(Z)-(2-Chlorophenyl)Methylidene]-4-(4-Methylphenyl)Piperazin-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, chiral purity (where applicable), and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.