Description

Pyrazolo[1,5-A]Pyridine-2-Carbonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci) is a high-value heterocyclic building block and key synthetic intermediate. Its core structure makes it a critical reagent for constructing complex molecular architectures in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fused pyrazole-pyridine scaffold.
• Organic Synthesis Building Block: The reactive carbonyl chloride group enables facile amide bond formation and other coupling reactions to create complex heterocyclic compounds.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules and activity-based probes for studying biological pathways and target engagement.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyridine-2-Carbonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci)
CAS No.	307313-04-8
Molecular Formula	C9H9ClN2O
Molecular Weight	196.63 g/mol
Synonyms	4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine-2-carbonyl chloride; 4,5,6,7-Tetrahydro-2-pyrazolo[1,5-a]pyridinecarbonyl chloride; 2-Pyrazolo[1,5-a]pyridinecarbonyl chloride, 4,5,6,7-tetrahydro-; Tetrahydro-pyrazolo[1,5-a]pyridine-2-carbonyl chloride; 307313-04-8; Pyrazolo[1,5-a]pyridine-2-carbonyl chloride, 4,5,6,7-tetrahydro-; 4,5,6,7-Tetrahydro-2H-pyrazolo[1,5-a]pyridine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyridine-2-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, NMR, and IR spectroscopy. We support cGMP compliance for advanced applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.