Description

3,4-Dihydro-2H-1,5-Benzodioxepine-7-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant value in advanced chemical synthesis. This compound serves as a critical building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is essential for research and development chemists and process engineers working on novel active ingredients, where its specific functional group enables precise chemical modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its benzodioxepine scaffold.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity intermediates.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	3,4-Dihydro-2H-1,5-Benzodioxepine-7-Carbonyl Chloride
CAS No.	306934-86-1
Molecular Formula	C11H9ClO3
Molecular Weight	224.64 g/mol
Synonyms	7-Chlorocarbonyl-3,4-dihydro-2H-1,5-benzodioxepine; 1,5-Benzodioxepine-7-carbonyl chloride, 3,4-dihydro-2H-; 3,4-Dihydro-2H-1,5-benzodioxepine-7-carboxylic acid chloride; 2H-1,5-Benzodioxepine-7-carbonyl chloride, 3,4-dihydro-; 7-Carboxybenzoyl chloride, 3,4-dihydro-2H-1,5-benzodioxepine-; Benzodioxepine carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-1,5-Benzodioxepine-7-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality commitment ensures reliable performance in your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.