Description

4-(2-Methoxyphenyl)-1-(2-Naphthylsulfonyl)Piperazine is a specialized piperazine derivative and sulfonamide compound, serving as a crucial building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which is designed for the development of novel pharmacologically active agents, particularly in central nervous system (CNS) and receptor-targeted research. This high-purity intermediate is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel drug candidates targeting neurological and psychiatric disorders.
• Chemical Biology Probe: Used in research to study protein-protein interactions and enzyme inhibition mechanisms due to its sulfonamide and piperazine motifs.
• Ligand Synthesis: Serves as a core structure for creating selective ligands for G-protein coupled receptors (GPCRs) and other biological targets.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract manufacturing and the production of non-commercial, proprietary compounds.

Basic Information

Item	Details
Product Name	4-(2-Methoxyphenyl)-1-(2-Naphthylsulfonyl)Piperazine
CAS No.	305373-59-5
Molecular Formula	C21H22N2O3S
Molecular Weight	382.48 g/mol
Synonyms	1-(Naphthalen-2-ylsulfonyl)-4-(2-methoxyphenyl)piperazine; 4-(2-Methoxyphenyl)-1-(naphthalene-2-sulfonyl)piperazine; 2-Methoxyphenyl-1-(2-naphthylsulfonyl)piperazine; N-(2-Naphthylsulfonyl)-4-(2-methoxyphenyl)piperazine; 305373-59-5; 4-(2-Methoxyphenyl)-1-(2-naphthylsulfonyl)piperazine; 1-(2-Naphthalenesulfonyl)-4-(2-methoxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyphenyl)-1-(2-Naphthylsulfonyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.