Description

Piperazine-1,4-Diylbis((2-Fluorophenyl)Methanone) is a high-purity, specialized organic compound featuring a central piperazine ring symmetrically substituted with 2-fluorobenzoyl groups. This molecular architecture makes it a valuable and versatile building block for advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. The compound serves as a critical intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioactivity-conferring piperazine and fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a scaffold for constructing chelating ligands in coordination chemistry and catalysis research.
• Polymer Science: Acts as a monomer or cross-linking agent for producing high-performance polymers with specific thermal and chemical resistance properties.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, or other functional organic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	Piperazine-1,4-Diylbis((2-Fluorophenyl)Methanone)
CAS No.	304510-78-9
Molecular Formula	C20H18F2N2O2
Molecular Weight	356.37 g/mol
Synonyms	1,4-Bis(2-fluorobenzoyl)piperazine; Bis(2-fluorophenyl)(piperazine-1,4-diyl)methanone; 2-Fluoro-1-[4-(2-fluorobenzoyl)piperazin-1-yl]phenylmethanone; Piperazine, 1,4-bis(2-fluorobenzoyl)-; 304510-78-9; 1,4-Piperazinediylbis[(2-fluorophenyl)methanone]
EINECS	Contact for details

Quality Control

Our Piperazine-1,4-Diylbis((2-Fluorophenyl)Methanone) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.