Description

1-[4-(4-Chlorophenyl)Piperazino]-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1-Propanone CAS NO 303148-36-9 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers for its role as a key building block in synthesizing potent and selective bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Agrochemical Research: Serves as a key structural component in the development of new-generation pesticides and herbicides.
• Chemical Biology Probe: Used in academic and industrial research to study biological pathways and protein-ligand interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-[4-(4-Chlorophenyl)Piperazino]-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1-Propanone
CAS No.	303148-36-9
Molecular Formula	C19H17Cl2F3N3O
Molecular Weight	434.26 g/mol
Synonyms	1-[4-(4-Chlorophenyl)piperazin-1-yl]-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]propan-1-one; 1-(4-(4-Chlorophenyl)piperazinyl)-2-(3-chloro-5-(trifluoromethyl)-2-pyridinyl)-1-propanone; 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(4-chlorophenyl)piperazin-1-yl)propan-1-one; CAS 303148-36-9; Propanone, 1-[4-(4-chlorophenyl)-1-piperazinyl]-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 303148-36-9
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Chlorophenyl)Piperazino]-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	≤ 2.0% total
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.