Description

1-Boc-4-(4-Methoxyphenyl)-4-Hydroxypiperidine CAS NO 302924-67-0 is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially within the central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for neurological and psychiatric disorders.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a protected amino-piperidine moiety.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery pipelines.
• Process Chemistry: Serves as a standardized starting material or intermediate in scale-up and optimization of manufacturing routes for target molecules.
• Chemical Biology Research: Utilized as a probe or precursor in the synthesis of compounds for studying biological pathways and target validation.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	1-Boc-4-(4-Methoxyphenyl)-4-Hydroxypiperidine
CAS No.	302924-67-0
Molecular Formula	C17H25NO4
Molecular Weight	307.39 g/mol
Synonyms	4-(4-Methoxyphenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4-methoxyphenyl)-4-hydroxypiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-methoxyphenyl)-4-hydroxypiperidine; 4-Hydroxy-4-(4-methoxyphenyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-methoxyphenyl)-4-hydroxypiperidine; 1-Boc-4-(p-Methoxyphenyl)-4-hydroxypiperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(4-Methoxyphenyl)-4-Hydroxypiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in cGMP and ISO-certified environments, ensuring reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.