Description

Nitric-15N-18O3 Acid is a stable isotope-labeled analog of nitric acid, where the nitrogen atom is enriched with the Nitrogen-15 isotope and the oxygen atoms are enriched with the Oxygen-18 isotope. This compound is an essential tool for advanced research and analytical applications, providing a non-radioactive tracer for studying reaction mechanisms, metabolic pathways, and environmental processes. It is primarily used by researchers and scientists in the fields of pharmaceutical development, environmental science, and analytical chemistry for precise isotopic labeling and mass spectrometry-based quantification.

Application

• Isotopic Tracer Studies: Used as a stable isotopic tracer in chemical reaction mechanism analysis and metabolic pathway research.
• Mass Spectrometry (MS) Standards: Serves as an internal standard or calibration standard in quantitative MS analysis, particularly in ICP-MS and LC-MS.
• Pharmaceutical Research: Employed in the synthesis and pharmacokinetic studies of labeled drug candidates and metabolites.
• Environmental Science: Applied in tracing nitrogen and oxygen cycles, nitrate source identification, and pollution studies.
• NMR Spectroscopy: Used in Nuclear Magnetic Resonance (NMR) studies due to the distinct magnetic properties of 15N and 18O nuclei.
• Geochemical Analysis: Utilized in isotopic analysis of geological samples to understand formation processes.
• Catalysis Research: Acts as a probe molecule in studies of catalytic oxidation and nitration reactions.
• Forensic Analysis: Supports isotopic fingerprinting in forensic investigations.

Basic Information

Product Name	Nitric-15N-18O3 Acid
CAS No.	302912-13-6
Molecular Formula	15N18O3H
Molecular Weight	67.00 g/mol (approx.)
Synonyms	Nitric-15N-18O3 Acid; [15N,18O3]-Nitric Acid; Nitric Acid-15N-18O3; Isotopic Nitric Acid; Labeled Nitric Acid; 15N,18O-Nitric Acid; Aqua Fortis-15N-18O3; Hydrogen [15N,18O3]nitrate
EINECS	Contact for details

Quality Control

Our Nitric-15N-18O3 Acid is produced under stringent conditions to ensure the highest isotopic and chemical purity. Each batch undergoes rigorous quality testing, including analysis by NMR, IR, and Isotope Ratio Mass Spectrometry (IRMS), to verify isotopic enrichment levels and chemical identity. Certificates of Analysis (COA) detailing the isotopic purity (atom % 15N and 18O), chemical purity, and assay are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as organic compounds, strong reducing agents, and bases. Due to its nature as a strong acid and strong oxidizer, ensure containers are clearly labeled and stored in a dedicated acid cabinet. Recommended long-term storage temperature is between 2°C and 8°C to maintain stability.

Specification

Item	Specification
Appearance	Colorless to faintly yellow liquid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 68.0% - 70.0%
15N Isotopic Purity	≥ 98 atom %
18O Isotopic Purity	≥ 95 atom % (per O atom)
Chemical Purity (HPLC)	≥ 99.0%
Chloride (Cl)	≤ 10 ppm
Sulfate (SO4)	≤ 20 ppm
Heavy Metals (as Pb)	≤ 5 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.