Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-Hydroxy-3-Methyl-, (8As)- (9Ci) is a high-purity, specialized heterocyclic compound with a defined stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate or chiral building block for the synthesis of complex active molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Utilized as a building block for constructing complex molecules with specific stereochemical configurations required for high biological activity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its unique fused pyrrolopyrazine-dione structure.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Academic & Industrial R&D: Used in chemical libraries for high-throughput screening and in methodological studies exploring new synthetic transformations.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-Hydroxy-3-Methyl-, (8As)- (9Ci)
CAS No.	302790-90-5
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	(8aS)-Hexahydro-3-hydroxy-3-methyl-pyrrolo[1,2-a]pyrazine-1,4-dione; (8aS)-3-Hydroxy-3-methylhexahydro-1H-pyrrolo[1,2-a]pyrazine-1,4-dione; Hexahydro-3-hydroxy-3-methyl-pyrrolo[1,2-a]pyrazine-1,4-dione, (8aS)-; 302790-90-5; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-hydroxy-3-methyl-, (8aS)-; (8aS)-3-Methyl-3-hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-Hydroxy-3-Methyl-, (8As)- (9Ci) adheres to stringent quality systems. The material is manufactured and controlled to meet exacting standards for pharmaceutical-grade intermediates, with a typical purity of ≥97% (by HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We ensure traceability and consistency to support your regulatory filings and process validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.