Description

2-Fluoro-α-Methyl-2-Methoxy-4-[(1E)-3-[4-(Nitrooxy)Butoxy]-3-Oxo-1-Propenyl]Phenyl Ester, [1,1'-Biphenyl]-4-Acetic Acid is a high-purity, complex organic ester with a specific molecular architecture designed for advanced chemical synthesis. This compound is valued for its role as a critical pharmaceutical intermediate and a versatile building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, particularly those targeting cardiovascular or inflammatory pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• API Synthesis: Serves as a sophisticated building block in multi-step synthetic routes for complex target molecules.
• Bioconjugation & Prodrug Development: The nitrooxy butoxy moiety can be leveraged in prodrug strategies or for creating targeted drug delivery systems.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high structural fidelity and purity.

Basic Information

Product Name	2-Fluoro-α-Methyl-2-Methoxy-4-[(1E)-3-[4-(Nitrooxy)Butoxy]-3-Oxo-1-Propenyl]Phenyl Ester, [1,1'-Biphenyl]-4-Acetic Acid
CAS No.	302543-79-9
Molecular Formula	C30H28FNO8
Molecular Weight	549.55 g/mol
Synonyms	2-Fluoro-α-methyl-2-methoxy-4-[(1E)-3-[4-(nitrooxy)butoxy]-3-oxo-1-propen-1-yl]phenyl [1,1'-biphenyl]-4-acetate; [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-2-methoxy-4-[(1E)-3-[4-(nitrooxy)butoxy]-1-oxo-1-propenyl]phenyl ester; 4'-Fluorophenyl Ester Derivative; NOB-Biphenyl Acetate Ester; 302543-79-9 (CAS Name); Biphenyl acetic acid fluoro methoxy nitrooxy propenyl ester.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant GMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.