Description

(R)-1-Benzyl-5-Methylpiperazin-2-One CAS NO 301541-47-9 is a high-purity chiral piperazinone derivative, a crucial building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for creating enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug development. This compound is essential for research institutions and pharmaceutical manufacturers focused on developing novel therapeutics with high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure drug candidates.
• CNS Drug Development: Used in research and production of potential treatments for neurological disorders.
• Antiviral Agent Synthesis: Serves as a building block for novel antiviral compounds.
• Asymmetric Catalysis Research: Employed as a ligand precursor or chiral auxiliary in catalytic processes.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry & Scale-Up: Used in developing and optimizing commercial-scale synthetic routes for APIs.

Basic Information

Product Name	(R)-1-Benzyl-5-Methylpiperazin-2-One
CAS No.	301541-47-9
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	(R)-1-Benzyl-5-methylpiperazin-2-one; (R)-1-Benzyl-5-methyl-2-piperazinone; (R)-5-Methyl-1-benzylpiperazin-2-one; (R)-1-Benzyl-5-methylpiperazin-2-one; (R)-1-Benzyl-5-methyl-2,3,4,5-tetrahydropyrazin-2-one; (R)-1-Benzyl-5-methyl-3,4-dihydro-2(1H)-pyrazinone; (R)-Benzyl-5-methylpiperazinone; (R)-BMPO
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-5-Methylpiperazin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to meet the stringent requirements of pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.