Description

1-(4-Benzylpiperazino)-2-Chloropropan-1-One is a high-purity synthetic organic compound featuring a piperazine core functionalized with benzyl and chloropropanone groups. This molecular architecture makes it a valuable key intermediate and building block in advanced chemical synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Chemical Synthesis: Functions as an alkylating agent or a key fragment in multi-step organic syntheses to introduce the 1-(4-benzylpiperazino)propan-1-one moiety.
• Biochemical Research: May be employed in the development of enzyme inhibitors or receptor ligands for biochemical and pharmacological assays.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	1-(4-Benzylpiperazino)-2-Chloropropan-1-One
CAS No.	301334-99-6
Molecular Formula	C14H19ClN2O
Molecular Weight	266.77 g/mol
Synonyms	2-Chloro-1-(4-benzylpiperazin-1-yl)propan-1-one; 1-(4-Benzyl-1-piperazinyl)-2-chloro-1-propanone; 2-Chloro-1-(4-benzylpiperazino)propan-1-one; 1-Propanone, 2-chloro-1-(4-benzyl-1-piperazinyl)-; 301334-99-6; 4-Benzyl-1-(2-chloropropanoyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Benzylpiperazino)-2-Chloropropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.