Description

1-(2-Nitro-Benzenesulfonyl)-Piperazine is a specialized sulfonamide derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific sulfonamide-piperazine motifs.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and protein-protein interactions.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Academic & Contract Research: Essential reagent for methodological development and novel reaction pathway exploration in university and CRO laboratories.

Basic Information

Product Name	1-(2-Nitro-Benzenesulfonyl)-Piperazine
CAS No.	301331-16-8
Molecular Formula	C10H13N3O4S
Molecular Weight	271.29 g/mol
Synonyms	1-(2-Nitrobenzenesulfonyl)piperazine; 2-Nitro-N-(piperazin-1-yl)benzenesulfonamide; Piperazine, 1-[(2-nitrophenyl)sulfonyl]-; 1-(2-Nitro-phenylsulfonyl)-piperazine; 2-Nitrobenzenesulfonyl piperazine; o-Nitrobenzenesulfonylpiperazine; NSC 405124; 301331-16-8
EINECS	Contact for details

Quality Control

Our 1-(2-Nitro-Benzenesulfonyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.