Description

2-Bromo-1-(1-Boc-Piperidin-4-Yl)Ethanone is a high-value, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the efficient construction of complex molecular scaffolds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Facilitates the incorporation of constrained piperidine motifs into peptide backbones to enhance stability and bioavailability.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Agrochemical Research: Used in the development of novel crop protection agents and pesticides.

Basic Information

Product Name	2-Bromo-1-(1-Boc-Piperidin-4-Yl)Ethanone
CAS No.	301221-79-4
Molecular Formula	C₁₂H₂₀BrNO₃
Molecular Weight	306.20 g/mol
Synonyms	1-(1-Boc-4-Piperidinyl)-2-Bromoethanone; 2-Bromo-1-[1-(tert-Butoxycarbonyl)-4-Piperidinyl]Ethanone; 1-(1-tert-Butoxycarbonylpiperidin-4-yl)-2-bromoethan-1-one; 2-Bromo-1-(1-Boc-4-piperidyl)ethanone; 2-Bromo-1-(N-Boc-piperidin-4-yl)ethanone; tert-Butyl 4-(2-Bromoacetyl)piperidine-1-carboxylate; N-Boc-4-(2-Bromoacetyl)piperidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(1-Boc-Piperidin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.