Description

4-[4-(tert-Butyl)Phenyl]-2-[4-(3-Chlorophenyl)Piperazino]-4-Oxobutanoic Acid is a high-purity, non-natural amino acid derivative featuring a complex molecular architecture with significant pharmaceutical research potential. This compound is valued for its role as a sophisticated synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and biochemical probes. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapeutic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of assays for studying enzyme inhibition or receptor binding.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the efficient, scalable production of complex molecules.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and methodological studies.
• Custom Synthesis Starting Material: Provides a versatile chiral scaffold for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Item	Detail
Product Name	4-[4-(tert-Butyl)Phenyl]-2-[4-(3-Chlorophenyl)Piperazino]-4-Oxobutanoic Acid
CAS No.	301194-14-9
Molecular Formula	C24H29ClN2O3
Molecular Weight	428.95 g/mol
Synonyms	2-[4-(3-Chlorophenyl)piperazin-1-yl]-4-[4-(tert-butyl)phenyl]-4-oxobutanoic acid; 4-Oxo-4-[4-(1,1-dimethylethyl)phenyl]-2-[4-(3-chlorophenyl)-1-piperazinyl]butanoic acid; Butanoic acid, 4-[4-(1,1-dimethylethyl)phenyl]-2-[4-(3-chlorophenyl)-1-piperazinyl]-4-oxo-; 4-(4-tert-Butylphenyl)-2-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxobutanoic acid; (RS)-2-[4-(3-Chlorophenyl)piperazin-1-yl]-4-[4-(tert-butyl)phenyl]-4-oxobutanoic acid
EINECS	Contact for details

Quality Control

Our 4-[4-(tert-Butyl)Phenyl]-2-[4-(3-Chlorophenyl)Piperazino]-4-Oxobutanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.