Description

Prothionamide-S-Oxide is a key pharmaceutical intermediate and metabolite of the anti-tuberculosis drug Prothionamide. This compound is critical for research and development in medicinal chemistry, particularly in the study of drug metabolism and the synthesis of novel therapeutic agents. It serves the needs of pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on infectious disease and analytical chemistry.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis and development of anti-tuberculosis (TB) medications and related analogs.
• Metabolite Reference Standard: Essential for analytical method development and validation in pharmacokinetic and bioequivalence studies for Prothionamide.
• Medicinal Chemistry Research: Used as a building block or precursor in the design and discovery of new antimicrobial agents.
• Quality Control & Testing: Serves as a high-purity standard in HPLC, LC-MS, and other analytical techniques for drug impurity profiling and assay development.
• Biochemical Research: Investigation of the mechanism of action and metabolic pathways of second-line TB drugs.

Basic Information

Product Name	Prothionamide-S-Oxide
CAS No.	39896-11-2
Molecular Formula	C₉H₁₂N₂OS
Molecular Weight	196.27 g/mol
Synonyms	2-Propylpyridine-4-carbothioamide S-oxide; Prothionamide Sulfoxide; Prothionamide S-Oxide; Ethionamide Sulfoxide (related analog); PTH-S-O; 2-Propylisonicotinothioamide S-oxide; 4-Pyridinecarbothioamide, 2-propyl-, S-oxide; 39896-11-2
EINECS	Contact for details

Quality Control

Our Prothionamide-S-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.