Description

Demethyl Benzydamine Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) with significant therapeutic potential. Its primary value lies in its role as a key synthetic precursor for the development of non-steroidal anti-inflammatory drugs (NSAIDs) and local anesthetic agents. This compound is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and manufacturers focused on producing advanced analgesic and anti-inflammatory medications.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of Benzydamine Hydrochloride and related analgesic APIs.
• Anti-inflammatory Drug Research: Used in R&D for developing new non-steroidal anti-inflammatory drugs (NSAIDs) with targeted mechanisms.
• Local Anesthetic Formulations: Serves as a building block for compounds with topical anesthetic and pain-relieving properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC, LC-MS, and NMR method development.
• Process Chemistry: Utilized in scale-up and optimization studies for commercial pharmaceutical manufacturing processes.
• Academic & Institutional Research: Used in universities and research institutes for pharmacological studies and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	Demethyl Benzydamine Hydrochloride
CAS No.	39860-97-4
Molecular Formula	C₁₉H₂₃N₃O•HCl
Molecular Weight	345.87 g/mol
Synonyms	1-Benzyl-3-(3-dimethylaminopropoxy)-1H-indazole Hydrochloride; Desmethyl Benzydamine HCl; Norbenzydamine Hydrochloride; 3-[(3-Dimethylamino)propoxy]-1-benzyl-1H-indazole Hydrochloride; Benzydamine Impurity; Benzydamine Related Compound A; LS-198; NSC-113295
EINECS	Contact for details

Quality Control

Our Demethyl Benzydamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.