Description

4-(Chlorocarbonyl)Benzoic Acid Butyl Ester is a versatile bifunctional organic intermediate containing both an acid chloride and an ester functional group. This compound is valued for its reactivity, serving as a key building block in the synthesis of more complex molecules, particularly in fine chemical and pharmaceutical manufacturing. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing active pharmaceutical ingredients (APIs), advanced materials, and liquid crystal compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a benzoic acid derivative scaffold.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its reactive groups allow for modular chemical construction.
• Liquid Crystal & OLED Materials: Serves as a building block for mesogenic units in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its rigid aromatic core.
• Polymer & Resin Modifier: Employed to introduce specific functional groups into polymer chains, enhancing properties like adhesion, solubility, or cross-linking capability.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and high-performance pigments.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions, such as Suzuki or Heck couplings, for creating biaryl structures common in advanced materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	4-(Chlorocarbonyl)Benzoic Acid Butyl Ester
CAS No.	39853-28-6
Molecular Formula	C12H13ClO3
Molecular Weight	240.68 g/mol
Synonyms	4-(Butoxycarbonyl)benzoyl chloride; Butyl 4-(chlorocarbonyl)benzoate; 4-Carboxybutyl benzoate chloride; Terephthalic acid monobutyl ester chloride; p-(Butoxycarbonyl)benzoyl chloride; 4-(Butoxycarbonyl)benzoyl chloride; Butyl terephthaloyl chloride (monoester)
EINECS	Contact for details

Quality Control

Our 4-(Chlorocarbonyl)Benzoic Acid Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis of the acid chloride group. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.