Description

4-(4-Trifluoromethyl-Phenyl)-Piperidin-4-Ol CAS NO 39757-71-6 is a high-value trifluoromethyl-substituted piperidine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring a piperidine ring with a hydroxyl group and a trifluoromethylphenyl substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and metabolic stability. This advanced pharmaceutical intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) drugs, receptor modulators, and other bioactive molecules.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Synthesis: Acts as a versatile building block in organic synthesis for constructing complex molecular architectures in medicinal chemistry programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	4-(4-Trifluoromethyl-Phenyl)-Piperidin-4-Ol
CAS No.	39757-71-6
Molecular Formula	C12H14F3NO
Molecular Weight	245.24 g/mol
Synonyms	4-(4-(Trifluoromethyl)phenyl)piperidin-4-ol; 4-Hydroxy-4-[4-(trifluoromethyl)phenyl]piperidine; 4-Piperidinol, 4-[4-(trifluoromethyl)phenyl]-; 4-(α,α,α-Trifluoro-p-tolyl)-4-piperidinol; 1-Boc-4-(4-trifluoromethylphenyl)-4-hydroxypiperidine (protected form); 4-(4-Trifluoromethylphenyl)-4-hydroxypiperidine
EINECS	Contact for details

Quality Control

Our 4-(4-Trifluoromethyl-Phenyl)-Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.