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1-(3-Chloropropyl)-Pyrrolidine CAS NO 39743-20-9


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CAS No.:39743-20-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(3-Chloropropyl)-Pyrrolidine is a versatile organic building block featuring both a pyrrolidine ring and a reactive chloropropyl side chain. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as building blocks for kinase inhibitors.
  • Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require a pyrrolidine-based moiety.
  • Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal complexation.
  • Chemical Research & Development: Employed in academic and industrial labs for exploring new heterocyclic compounds and conducting structure-activity relationship (SAR) studies.
  • Material Science: Potential monomer or modifier in the synthesis of specialty polymers and functional materials.

Basic Information

Product Name 1-(3-Chloropropyl)-Pyrrolidine
CAS No. 39743-20-9
Molecular Formula C7H14ClN
Molecular Weight 147.65 g/mol
Synonyms N-(3-Chloropropyl)pyrrolidine; 3-(Pyrrolidin-1-yl)propyl chloride; 1-Chloro-3-(pyrrolidin-1-yl)propane; Pyrrolidine, 1-(3-chloropropyl)-; 3-Chloro-N-propylpyrrolidine; 3-Pyrrolidin-1-ylpropyl chloride; N-(3-Chloropropyl)azacyclopentane
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Quality Control

Our 1-(3-Chloropropyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 0.5%
Refractive Index (n20D) 1.470 - 1.480
Density (g/mL, 20°C) 1.00 - 1.05

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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