Description

Ergotoxine Methanesulfonate is a high-purity pharmaceutical-grade alkaloid salt, specifically the methanesulfonate salt of ergotoxine. This compound is valued for its consistent potency and stability, making it a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by the pharmaceutical industry for the development and quality control of specialized medications, particularly in the field of neurology and vascular therapeutics.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification and assay of related ergot alkaloids in drug substances and finished products.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the controlled synthesis of complex therapeutic agents targeting neurological and vascular systems.
• Biochemical Research: Employed in in-vitro studies to investigate its mechanism of action on adrenergic and serotonin receptors.
• Quality Control & Analytical Testing: Essential for HPLC and other chromatographic methods to ensure the purity and consistency of ergot-derived pharmaceuticals.
• Formulation Development: Used in R&D for developing stable dosage forms, leveraging its salt form for improved solubility and handling characteristics.

Basic Information

Product Name	Ergotoxine Methanesulfonate
CAS No.	39435-95-5
Molecular Formula	C35H41N5O6 · CH4O3S
Molecular Weight	723.82 g/mol
Synonyms	Ergotoxine Mesylate; Ergotoxine Methanesulphonate; Dihydroergotoxine Methanesulfonate; Ergoloid Mesylates (component); 9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione methanesulfonate; Co-dergocrine Mesylate (related mixture); Hydergine component (related mixture)
EINECS	Contact for details

Quality Control

Our Ergotoxine Methanesulfonate is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our global clientele in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.