Description

Phosphatidylethanolamine CAS NO 39382-08-6 is a naturally occurring phospholipid and a fundamental component of biological membranes. Its unique amphiphilic structure makes it a critical material for creating liposomes and lipid nanoparticles, which are essential for advanced drug delivery systems. This high-purity phospholipid is indispensable for research and manufacturing in the pharmaceutical, nutraceutical, and cosmetic industries, where it serves as a key excipient and bioactive agent.

Application

• Pharmaceutical Excipient: A primary component in the formulation of liposomes and lipid nanoparticles (LNPs) for targeted drug and gene delivery (e.g., mRNA vaccines).
• Cell Culture & Research: Used in cell membrane studies, as a supplement in serum-free media, and for investigating apoptosis and cell signaling pathways.
• Nutraceutical Encapsulation: Employed to create liposomal supplements for enhanced bioavailability of vitamins, coenzyme Q10, and other active ingredients.
• Cosmetic Formulations: Acts as a natural emollient and skin-identical lipid in high-end creams and serums to improve skin barrier function and delivery of actives.
• Biochemical Reagent: Serves as a substrate for enzymes like phospholipase D and in the study of lipid metabolism.
• Diagnostic Kits: Used in the production of reagents for clinical diagnostics, particularly in assays involving membrane fusion or stability.

Basic Information

Product Name	Phosphatidylethanolamine
CAS No.	39382-08-6
Molecular Formula	C41H82NO8P (for a common species, e.g., DOPE)
Molecular Weight	~744.08 g/mol (for DOPE)
Synonyms	PE; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE); Phosphatidylethanolamine (soy); Cephalin; (3-sn-Phosphatidyl)ethanolamine; L-α-Phosphatidylethanolamine; PtdEtn; EINECS 254-438-0
EINECS	254-438-0

Quality Control

Our Phosphatidylethanolamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and lipid profile analysis, TLC for identification, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards (USP/EP) for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. For short-term use, vials may be stored at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to light yellow waxy solid or powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0% (Total Phosphatidylethanolamine)
Loss on Drying	≤ 2.0 %
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	≤ 10 ppm
Peroxide Value	≤ 3.0 meq/kg
Fatty Acid Composition (GC)	Report (Typical: High Oleic Acid content)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.