Description

Chenodeoxycholic Acid Sulfate Conjugate is a sulfated derivative of the primary bile acid, chenodeoxycholic acid. This modification enhances its water solubility and alters its biological activity, making it a critical intermediate and reference standard for advanced research and development. It is essential for scientists and manufacturers in the pharmaceutical and life science sectors. This compound is particularly valuable for studying bile acid metabolism, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and pharmacokinetic studies.
• Metabolic Research: A key tool for investigating the sulfation pathway of bile acids and its role in liver function and cholestatic diseases.
• Drug Discovery & Development: Serves as a crucial intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel hepatoprotective or metabolic disorder therapeutics.
• Biochemical Assays: Employed in enzyme activity studies (e.g., sulfotransferases) and receptor binding assays to understand specific biological interactions.
• Diagnostic Kit Manufacturing: Utilized in the production of diagnostic reagents and kits for detecting and quantifying bile acid profiles in clinical samples.

Basic Information

Product Name	Chenodeoxycholic Acid Sulfate Conjugate
CAS No.	39280-88-1
Molecular Formula	C24H40O7S
Molecular Weight	472.63 g/mol
Synonyms	3α,7α-Dihydroxy-5β-cholan-24-oic Acid 7-Sulfate; Chenodeoxycholic Acid 7-Sulfate; 7-Sulfochendesoxycholic Acid; CDCA Sulfate; 7α-Sulfolithocholic Acid; 3α,7α-Dihydroxy-5β-cholanoic Acid 7-Sulfate; Taurochenodeoxycholic Acid Sulfate (related conjugate); Cholanoic Acid, 3,7-dihydroxy-, 7-sulfate, (3α,5β,7α)-
EINECS	Contact for details

Quality Control

Our Chenodeoxycholic Acid Sulfate Conjugate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.