Description

1-Thiophen-2-Ylmethyl-Piperazine is a versatile heterocyclic building block and intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a piperazine ring and a thiophene moiety, makes it a critical precursor for the development of novel pharmacologically active compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents, receptor modulators, and other bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal complexation studies.
• Material Science: Employed in the research of organic electronic materials, polymers, and dyes due to the electron-rich thiophene component.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the design of molecular probes and tool compounds for biological target identification.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-Thiophen-2-Ylmethyl-Piperazine
CAS No.	39244-79-6
Molecular Formula	C9H14N2S
Molecular Weight	182.29 g/mol
Synonyms	1-[(Thiophen-2-yl)methyl]piperazine; 2-(Piperazin-1-ylmethyl)thiophene; 1-(Thiophen-2-ylmethyl)piperazine; Piperazine, 1-[(2-thienyl)methyl]-; 39244-79-6; Thiophen-2-ylmethyl-piperazine; (Thiophen-2-ylmethyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Thiophen-2-Ylmethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP or ISO 9001 standards for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.