Description

(Chloromethyl)Pyrazine is a versatile heterocyclic building block featuring a reactive chloromethyl group attached to a pyrazine ring. This compound is highly valued in organic synthesis for its ability to introduce the pyrazine moiety into more complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides where the pyrazine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the creation of novel organic electronic materials and metal-organic frameworks (MOFs).
• Flavor and Fragrance Industry: Acts as an intermediate for synthesizing complex aroma compounds, given the significance of alkylpyrazines in flavor chemistry.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(Chloromethyl)Pyrazine
CAS No.	39204-47-2
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	2-(Chloromethyl)pyrazine; Pyrazine, 2-(chloromethyl)-; 2-Chloromethylpyrazine; (2-Pyrazinyl)methyl chloride; 2-Pyrazinemethanol, chloride; 39204-47-2; Chloromethylpyrazine
EINECS	Contact for details

Quality Control

Our (Chloromethyl)Pyrazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.