Description

Taurobilirubin CAS NO 39084-19-0 is a conjugated form of bilirubin, specifically the taurine amide derivative. This compound is of significant interest in biochemical research and diagnostic development due to its role as a key metabolite in bile pigment metabolism. It serves as a crucial reference standard and intermediate for researchers and manufacturers in the pharmaceutical and diagnostic industries, particularly those focused on liver function, jaundice, and metabolic disorders.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for studying bilirubin conjugation, transport, and metabolism pathways.
• Diagnostic Reagent Development: Serves as a critical calibrant and component in the formulation of clinical diagnostic kits for measuring conjugated bilirubin in serum.
• Pharmaceutical Intermediates: Acts as a key starting material or intermediate in the synthesis of novel therapeutic agents targeting liver diseases and bile duct disorders.
• Metabolite Analysis: Essential for method development and validation in analytical techniques like HPLC and LC-MS for accurate quantification of bile pigments in biological samples.
• Enzymology Studies: Employed as a specific substrate for research on enzymes like UDP-glucuronosyltransferases (UGTs) and bilirubin reductases.
• Toxicology & Drug Safety: Used in investigations of drug-induced liver injury (DILI) and the impact of xenobiotics on bilirubin conjugation and excretion.

Basic Information

Product Name	Taurobilirubin
CAS No.	39084-19-0
Molecular Formula	C₄₅H₆₄N₆O₉S
Molecular Weight	865.1 g/mol
Synonyms	Bilirubin Taurine Conjugate; Tauro-conjugated Bilirubin; 2-[[(2Z)-2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-1H-pyrrol-2-yl)methyl]-4-methyl-1H-pyrrol-2-yl]methylidene]-5-[(3-ethenyl-4-methyl-5-oxo-1H-pyrrol-2-yl)methyl]-4-methyl-1H-pyrrol-3-yl]acetamido]ethanesulfonic Acid; Taurine Bilirubin Amide; Conjugated Bilirubin (Taurine); (Z,Z)-Taurobilirubin
EINECS	Contact for details

Quality Control

Our Taurobilirubin is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC purity, impurity profile) are provided to guarantee reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider inert atmosphere conditions to prevent potential oxidation.

Specification

Item	Specification
Appearance	Orange to brown powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.