Description

[R,(-)]-3-Hydroxy-4-Pentenoic Acid is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its enantiomerically pure form provides a critical scaffold for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, antiviral agents, and other bioactive molecules requiring precise stereocontrol.
• Asymmetric Synthesis: Used as a starting material or building block in catalytic asymmetric reactions to introduce the (R)-3-hydroxy-4-pentenoyl moiety.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced polymer precursors.
• Academic & Industrial Research: Serves as a valuable reagent in methodological development for organic and medicinal chemistry research.
• Agrochemical Synthesis: Potential intermediate for creating chiral active ingredients with specific biological activity.

Basic Information

Product Name	[R,(-)]-3-Hydroxy-4-Pentenoic Acid
CAS No.	38996-04-2
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(R)-3-Hydroxy-4-pentenoic acid; (R)-(-)-3-Hydroxy-4-pentenoic acid; (3R)-3-Hydroxypent-4-enoic acid; (R)-3-Hydroxy-4-pentenoic acid; D-(-)-3-Hydroxy-4-pentenoic acid; (R)-3-Hydroxy-4-pentenoate; (R)-HPA
EINECS	Contact for details

Quality Control

Our [R,(-)]-3-Hydroxy-4-Pentenoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with full specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow liquid/oil
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Enantiomeric Purity (Chiral HPLC)	≥98.0% e.e.
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.