Description

Filipin I CAS NO 38723-93-2 is a polyene macrolide antibiotic complex, specifically a major component of the filipin mixture, known for its potent antifungal properties. This compound is a critical tool in biochemical research for its ability to bind to membrane sterols, particularly cholesterol, making it invaluable for studying membrane structure and function. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from antifungal agent development to fundamental cell biology studies.

Application

• Antifungal Research: Serves as a reference standard and active agent in the study of antifungal mechanisms and the development of novel therapeutic candidates.
• Membrane Biology Studies: Used extensively as a fluorescent probe to visualize and investigate the distribution and role of cholesterol in cellular and model membranes.
• Biochemical Reagent: Employed in laboratory settings to disrupt membrane integrity for cell lysis or to study sterol-dependent processes.
• Pharmaceutical Intermediates: Acts as a key starting material or reference compound in the synthesis and quality control of more complex polyene antibiotics.
• Academic & Industrial R&D: Essential for basic research in microbiology, mycology, and lipid biochemistry within universities, research institutes, and corporate R&D departments.

Basic Information

Product Name	Filipin I
CAS No.	38723-93-2
Molecular Formula	C35H58O11
Molecular Weight	654.83 g/mol
Synonyms	Filipin I; Filipin III; NSC 262445; Antibiotic X-73; U-5956; Filipin complex component I; 28,29-Didehydromacrolidin; (1R,3S,5R,7R,8E,12E,14E,16E,18R,19R,20R,21R,23S,24E,26E)-19,21-Dihydroxy-3,5,7,11,15,23-hexamethyl-26-[(1E)-1-methyl-2-(2-methyl-1,3-dioxolan-2-yl)ethenyl]-2,6,10,14,22-pentaoxaheptacyclo[13.9.1.1³,⁷.1⁸,¹².0¹,²³.0¹⁵,²⁰.0¹⁹,²⁴]nonacosa-8,12,14,16,24,26-hexaene-4,13-dione
EINECS	Contact for details

Quality Control

Our Filipin I is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation. A detailed Certificate of Analysis (COA) documenting purity, identity, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. The product is light-sensitive (store away from light). Allow the container to reach room temperature before opening to minimize moisture condensation. Keep under inert atmosphere if specified for the specific grade.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.