Description

2-Chloro-6-Methylpyrazine is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those with pyrazine-based core structures.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides where the chloromethylpyrazine moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands used in coordination chemistry and catalytic processes.
• Flavor and Fragrance Industry: Acts as a key intermediate for synthesizing complex aroma compounds, contributing to roasted, nutty, or earthy notes.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	2-Chloro-6-Methylpyrazine
CAS No.	38557-71-0
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	6-Methyl-2-chloropyrazine; 2-Chloro-6-picoline; 2-Chloro-6-methyl-1,4-diazine; Chloromethylpyrazine; Pyrazine, 2-chloro-6-methyl-; 2-Chloro-6-methylpyrazine (primary name)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylpyrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.