Description

2,2,6,6-Tetramethyl-Piperazine is a high-purity, sterically hindered piperazine derivative of significant industrial importance. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly valued for its role in creating complex molecular architectures. It is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality intermediates for catalyst systems, ligand synthesis, and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring hindered amine frameworks for stability or specific biological activity.
• Catalyst & Ligand Synthesis: Used to construct sophisticated ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polymers, including polyamides and polyurethanes, where its structure can impart desired thermal or mechanical properties.
• Agrochemical Synthesis: Employed in the development of advanced herbicides, fungicides, and pesticides that require a stable, nitrogen-containing heterocyclic core.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.
• Corrosion Inhibitor Formulation: Used as a component in specialty formulations designed to protect metals in challenging environments.

Basic Information

Product Name	2,2,6,6-Tetramethyl-Piperazine
CAS No.	38515-26-3
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	2,2,6,6-Tetramethylpiperazine; TMP; 2,2,6,6-Tetramethylhexahydropyrazine; Hexahydro-2,2,6,6-tetramethylpyrazine; NSC 163049; Perhydro-2,2,6,6-tetramethylpyrazine; 1,4-Diazabicyclo[2.2.2]octane, 2,2,6,6-tetramethyl- (related bicyclic system)
EINECS	Contact for details

Quality Control

Our 2,2,6,6-Tetramethyl-Piperazine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC and HPLC, to monitor critical parameters such as assay and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.