Description

5α-Pregnane-3β,20-Diol is a high-purity steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of therapeutic agents, reference standards, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of steroidal drugs and hormones.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Biochemical Research: Employed in metabolic pathway studies and as a substrate for investigating enzyme activity related to steroid metabolism.
• API Development: Serves as a starting material or intermediate in the research and scale-up production of new chemical entities (NCEs).
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized steroid derivatives.

Basic Information

Product Name	5α-Pregnane-3β,20-Diol
CAS No.	38270-91-6
Molecular Formula	C21H36O2
Molecular Weight	320.51 g/mol
Synonyms	5α-Pregnane-3β,20α-diol; 20α-Hydroxy-5α-pregnan-3β-ol; 3β,20α-Dihydroxy-5α-pregnane; Allopregnanediol; 5α-Pregnan-3β,20α-diol
EINECS	Contact for details

Quality Control

Our 5α-Pregnane-3β,20-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, GC, and NMR, to ensure it meets the high standards required for pharmaceutical intermediates and research chemicals. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.