Description

1-tert-Butylpiperazine is a versatile and valuable piperazine derivative, widely recognized for its role as a key building block in advanced organic synthesis. Its significance lies in its ability to introduce the sterically hindered tert-butylpiperazine moiety, which is crucial for modulating the physicochemical and pharmacological properties of target molecules. This high-purity intermediate is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) agents and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the tert-butylpiperazine group can enhance biological activity and stability.
• Organic Synthesis Reagent: Serves as a valuable amine component in nucleophilic substitution, condensation, and coupling reactions to create complex molecular architectures.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis and organocatalysts for asymmetric synthesis.
• Chemical Research & Development: A fundamental tool in medicinal chemistry and process chemistry for exploring structure-activity relationships (SAR) and optimizing synthetic routes.
• Fine Chemical Production: Integral to the manufacture of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	1-tert-Butylpiperazine
CAS No.	38216-72-7
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	N-tert-Butylpiperazine; 1-(1,1-Dimethylethyl)piperazine; 1-(tert-Butyl)piperazine; tert-Butylpiperazine; N-t-Butylpiperazine; 1-(2-Methyl-2-propanyl)piperazine; Piperazine, 1-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our 1-tert-Butylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify purity and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.