Description

Sulindac is a non-steroidal anti-inflammatory drug (NSAID) belonging to the arylalkanoic acid class, widely recognized for its potent anti-inflammatory, analgesic, and antipyretic properties. Its primary commercial value lies in its role as a key active pharmaceutical ingredient (API) for the formulation of prescription medications. This compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for conditions such as osteoarthritis, rheumatoid arthritis, and acute gouty arthritis. Sulindac CAS NO 38194-50-2 represents a critical building block in the global pharmaceutical supply chain, where consistent quality and reliable sourcing are paramount.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription anti-inflammatory and analgesic drug formulations.
• Generic Drug Manufacturing: Sourcing for the production of generic sulindac tablets for global markets.
• Clinical Research: Utilization in preclinical and clinical studies for investigating new therapeutic applications or formulations.
• Analytical Reference Standard: Serves as a high-purity standard in quality control (QC) and analytical laboratories for HPLC, LC-MS, or pharmacopeial testing.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing pain and inflammation in animals.
• Biochemical Research: Used in studies exploring COX enzyme inhibition mechanisms and related biochemical pathways.

Basic Information

Product Name	Sulindac
CAS No.	38194-50-2
Molecular Formula	C20H17FO3S
Molecular Weight	356.41 g/mol
Synonyms	(Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid; Clinoril; Arthrocine; Imbaral; Zulida; Aflodac; Sulindacum; MK-231
EINECS	253-821-8

Quality Control

Our Sulindac is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against relevant pharmacopeial specifications (such as USP/EP) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing results for key parameters including assay, related substances, residual solvents, and heavy metals. We are committed to supply chain transparency and regulatory compliance (including ICH Q7 and cGMP guidelines where applicable) to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Yellow crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.