Description

Carboxy Gliclazide is a key pharmaceutical intermediate and metabolite of the sulfonylurea drug Gliclazide. This compound is of significant value for research and development in the pharmaceutical industry, particularly in the study of drug metabolism and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories focused on diabetes treatment and metabolic research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and research of Gliclazide and its related analogs.
• Metabolite Reference Standard: Used as a certified reference material (CRM) in bioanalytical studies for quantifying Gliclazide metabolites in biological samples.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor or model compound in the development of new sulfonylurea-based therapeutics.
• Quality Control & Analytical Testing: Employed in HPLC, LC-MS, and other analytical methods for method development and validation within pharmaceutical QC labs.
• Pharmacokinetic & Pharmacodynamic Studies: Essential for understanding the absorption, distribution, metabolism, and excretion (ADME) profile of Gliclazide.
• Academic & Institutional Research: Used in universities and research institutes for studies on diabetes, insulin secretion, and drug metabolism pathways.

Basic Information

Product Name	Carboxy Gliclazide
CAS No.	38173-52-3
Molecular Formula	C15H21N3O4S
Molecular Weight	339.41 g/mol
Synonyms	1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-(4-carboxyphenyl)sulfonylurea; Gliclazide Carboxylic Acid; Gliclazide Metabolite; M1 Metabolite of Gliclazide; Gliclazide-COOH; 3-{[(4-Carboxyphenyl)sulfonyl]carbamoyl}hexahydro-1H-pyrrolizin-1-ium; UNII-7VJ280552I
EINECS	Contact for details

Quality Control

Our Carboxy Gliclazide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis to ensure it meets high-purity standards suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.