Description

1-Phenyl-4-(Piperazine-1-Carbonyl)Pyrrolidin-2-One Hydrochloride is a high-purity organic salt compound with significant synthetic utility. Its value lies in its role as a versatile and critical pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). This compound is essential for manufacturers and research organizations in the pharmaceutical and biotechnology sectors focused on creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and other therapeutic areas.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for the research and production of new APIs.
• Chemical Synthesis Research: Used in academic and industrial R&D laboratories for exploring new synthetic pathways and creating novel chemical entities.
• Preclinical and Clinical Trial Material: Supplied as a high-purity intermediate for the production of compounds used in drug discovery and development stages.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	1-Phenyl-4-(Piperazine-1-Carbonyl)Pyrrolidin-2-One Hydrochloride
CAS No.	38160-15-5
Molecular Formula	C15H19N3O2 • HCl
Molecular Weight	309.79 g/mol (Free base: 273.33 g/mol)
Synonyms	1-Phenyl-4-(piperazine-1-carbonyl)pyrrolidin-2-one HCl; 4-(Piperazine-1-carbonyl)-1-phenylpyrrolidin-2-one hydrochloride; 1-Phenyl-4-(piperazinecarbonyl)-2-pyrrolidinone hydrochloride; 2-Pyrrolidinone, 1-phenyl-4-(1-piperazinylcarbonyl)-, hydrochloride; UNII-8I1J6Q2Q1F; 8I1J6Q2Q1F; 1-Phenyl-4-(piperazine-1-carbonyl)-2-pyrrolidinone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Phenyl-4-(Piperazine-1-Carbonyl)Pyrrolidin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.